Research Questions

What are the risk factors for clinical coronary heart disease and stroke among persons with subclinical cardiovascular disease (CVD)?

• What are the risk factors among persons with varying levels of subclinical atherosclerosis (for example, among those with the greatest burden of atherosclerosis) and other forms of subclinical CVD?

• Does the risk associated with these factors vary among different gender and ethnicity subgroups?

• Are there new CVD risk factors that are important predictors after accounting for the effects of established risk factors?

What are the risk factors for progression of subclinical atherosclerosis and other forms of subclinical CVD?

• Are there new risk factors that are important predictors after accounting for the effect of traditional risk factors?

• Does the risk associated with these factors vary among different gender and ethnicity subgroups?

• What are the risk factors for progression of subclinical CVD, particularly atherosclerosis, among those with different levels of baseline subclinical CVD?